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・ Trimeresurus purpureomaculatus
・ Trimeresurus purpureomaculatus andersoni
・ Trimeresurus rubeus
・ Trimeresurus schultzei
・ Trimeresurus stejnegeri
・ Trimeresurus stejnegeri chenbihuii
・ Trimeresurus stejnegeri yunnanensis
・ Trimeresurus strigatus
・ TRIM16
・ TRIM21
・ TRIM22
・ TRIM23
・ TRIM24
・ TRIM25
・ TRIM27
TRIM28
・ TRIM29
・ TRIM3
・ TRIM31
・ TRIM32
・ TRIM33
・ TRIM37
・ TRIM41
・ TRIM45
・ TRIM50
・ TRIM55
・ TRIM5alpha
・ TRIM6
・ TRIM62
・ TRIM63


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TRIM28 : ウィキペディア英語版
TRIM28

Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the ''TRIM28'' gene.
== Function ==
The protein encoded by this gene mediates transcriptional control by interaction with the Krüppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10155 )
KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, cellular differentiation and proliferation, DNA damage repair, viral suppression, and apoptosis.(4) Its functionality is dependent upon post-translational modifications. Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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