翻訳と辞書 Words near each other ・ Tru-la-lá ・ Tru-Paz ・ TRU-SPEC ・ Tru-Vue ・ Tru2way ・ Tru64 UNIX ・ Truancy ・ Truancy (novel) ・ Truancy Intervention Project, Inc. ・ Truant (album) ・ Truant (disambiguation) ・ Truant (steamboat) ・ Truant / Rough Sleeper ・ TRPM ・ TRPM1 ・ TRPM2 ・ TRPM3 ・ TRPM4 ・ TRPM5 ・ TRPM6 ・ TRPM7 ・ TRPM8 ・ TRPML ・ TRPN ・ TRPP ・ TRPP3 ・ TRPT1 ・ TRPV ・ TRPV1 ・ TRPV2 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク TRPM2 ： ウィキペディア英語版 TRPM2 Transient receptor potential cation channel, subfamily M, member 2, also known as TRPM2, is a protein that in humans is encoded by the ''TRPM2'' gene. == Function == The ''TRPM2'' gene is highly expressed in the brain and was implicated by both genetic linkage studies in families and then by case control or trio allelic association studies in the genetic aetiology of bipolar affective disorder (Manic Depression). The physiological role of TRPM2 is not well understood. It was shown to be involved in insulin secretion.〔 In the immune cells it mediates parts of the responses to TNF-alpha. A role has been suggested for TRPM2 in activation of NLRP3 inflammasome, the dysregulation of which is strongly associated with a number of auto inflammatory and metabolic diseases, such as gout, obesity and diabetes. In the brain it is involved in the toxicity of amyloid beta, a protein associated with Alzheimer's disease. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「TRPM2」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.