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Tabalumab
Tabalumab (LY 2127399) is an anti-B-cell activating factor (BAFF) human monoclonal antibody designed for the treatment of autoimmune diseases and B cell malignancies.〔(【引用サイトリンク】publisher=American Medical Association )〕〔http://www.lillyoncologypipeline.com/Pages/baff-antibody.aspx〕 Tabalumab was developed by Eli Lilly and Company. A phase III clinical trial for rheumatoid arthritis was halted in Feb 2013.〔http://lilly.mediaroom.com/index.php?s=9042&item=136985〕 In September 2014, a second phase III trial focussing on treating systemic lupus erythematosus, was terminated early as the study failed to meet its primary endpoint.〔http://www.genengnews.com/gen-news-highlights/lilly-halts-tabalumab-development-for-lupus/81250423/〕 == References == 〔
Now dropped by Lilly due to lack of efficacy.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Tabalumab」の詳細全文を読む
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