|
Tableting is a method of confectionery manufacture that shares many similarities with tablet pharmaceutical production. A powder or granule mixture is prepared, a die mold is filled, and then the mixture is compressed and ejected. While drug tablets are constrained to shapes that can be swallowed easily, candy tablets are chewable. ==Introduction== The manufacture of oral solid dosage forms such as tablets is a complex multi-stage process under which the starting materials change their physical characteristics a number of times before the final dosage form is produced. Traditionally, tablets have been made by granulation, a process that imparts two primary requisites to formulate: compactibility and fluidity. Both wet granulation and dry granulation (slugging and roll compaction) are used. Regardless of whether tablets are made by direct compression or granulation, the first step, milling and mixing, is the same; subsequent steps differ. Numerous unit processes are involved in making tablets, including particle size reduction and sizing, blending, granulation, drying, compaction, and (frequently) coating. Various factors associated with these processes can seriously affect content uniformity, bioavailability, or stability. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Tableting」の詳細全文を読む スポンサード リンク
|