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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Tafenoquine ： ウィキペディア英語版 Tafenoquine Tafenoquine is an 8-aminoquinoline drug manufactured by GlaxoSmithKline that is being investigated as a potential treatment for malaria, as well as for malaria prevention. The proposed indication for tafenoquine is for treatment of the hypnozoite stages of ''Plasmodium vivax'' and ''Plasmodium ovale'' that are responsible for relapse of these malaria species even when the blood stages are successfully cleared. This is only now achieved by administration of daily primaquine for 14 days. The main advantage of tafenoquine is that it has a long half-life (2–3 weeks) and therefore a single treatment may be sufficient to clear hypnozoites. The shorter regimen has been described as an advantage. Like primaquine, tafenoquine causes hemolysis in people with G-6-P deficiency.〔 Indeed, the long half-life of tafenoquine suggests that particular care should be taken to ensure that individuals with severe G-6-P deficiency do not receive the drug. The dose of tafenoquine has not been firmly established, but for the treatment of ''Plasmodium vivax'' malaria, a dose of 800 mg over three days has been used. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Tafenoquine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.