翻訳と辞書 |
Taipoxin Taipoxin is an extremely potent neurotoxin developed by purifying the venom of the Australian taipan ''Oxyuranus scutellatus''.〔J. Fohlman, D. Eaker, E. Karlsoon, S. Thesleff: ''Taipoxin, an extremely potent presynaptic neurotoxin from the venom of the australian snake taipan (Oxyuranus s. scutellatus). Isolation, characterization, quaternary structure and pharmacological properties.'' Eur. J. Biochem. 1976 Sep 15;68(2):457-69.〕 The toxin causes a gradual reduction to complete cessation of evoked and spontaneous release of acetylcholine from motor nerve terminals. The victim dies from asphyxia caused by paralysis of the respiratory muscles. It is the most lethal neurotoxin isolated from any snake venom to date. The molecular mass of the heterotrimer is about 35,000 Dalton; comprising 1:1:1 α, β and γ monomers.〔Alomone labs: (''Taipoxin'' (pdf) )〕 Median lethal dose for mice was determined as 2 μg/kg (subcutaneous injection).〔 == References == 〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Taipoxin」の詳細全文を読む
スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|