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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Taranabant ： ウィキペディア英語版 Taranabant Taranabant (codenamed MK-0364) is a cannabinoid receptor type 1 inverse agonist being investigated as a potential treatment for obesity due to its anorectic effects.〔Armstrong HE, Galka A, Lin LS, Lanza TJ Jr, Jewell JP, Shah SK, et al. "Substituted acyclic sulfonamides as human cannabinoid-1 receptor inverse agonists." ''Bioorganic & Medicinal Chemistry Letters''. 2007 Apr 15;17(8):2184-7. PMID 17293109. 〕〔Fong TM, Guan XM, Marsh DJ, Shen CP, Stribling DS, Rosko KM, et al. "Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N--2-methyl-2-()oxy]propanamide (MK-0364), in rodents." ''Journal of Pharmacology and Experimental Therapeutics''. 2007 Jun;321(3):1013-22. PMID 17327489. 〕 It was discovered by Merck & Co. In October 2008, Merck has stopped its phase III clinical trials with the drugs due to high level of central side effects, mainly depression and ()].〔(【引用サイトリンク】title=Press release by Merck )〕 == See also == * Cannabinoid receptor antagonist 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Taranabant」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.