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Tenatoprazole : ウィキペディア英語版
Tenatoprazole

Tenatoprazole is a proton pump inhibitor drug candidate that was undergoing clinical testing as a potential treatment for reflux oesophagitis and peptic ulcer as far back as 2003.〔DataMonitor. March 2003. (Gastrointestinal Disease Update: Digestive Disease Week 2003 )〕 The compound was invented by Mitsubishi Tanabe Pharma and was licensed to Negma Laboratories (part of Wockhardt as of 2007〔Economic Times. 3 March, 2011. (Investors unwilling to forgive Wockhardt, promoter for failings )〕).〔
Mitsubishi reported that tenatoprazole was still in Phase I clinical trials in 2007〔Mitsubishi Tanabe Pharma (FY2007 Interim Financial Results )〕 and again in 2012.〔Mitsubishi Tanabe Pharma (State of New Product Development (as of May 8, 2012) )〕
Tenatoprazole has an imidazopyridine ring in place of the benzimidazole moiety found in other proton pump inhibitors, and has a half-life about seven times longer than other PPIs.〔Li H et al. H+/K+-ATPase inhibitors: a patent review. Expert Opin Ther Pat. 2013 Jan;23(1):99-111. PMID 23205582〕
== References ==


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