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Teschovirus
''Teschovirus'' is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Pigs serve as natural hosts. There is currently only one species in this genus: the type species ''Teschovirus A'' (previously ''Porcine teschovirus''), which is responsible for the porcine enteroviral encephalomyelitis disease caused in pigs. 〔(【引用サイトリンク】url=http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/102100.htm )〕 The genus name comes from its type species and the disease it causes: Teschen disease (a severe and fatal form of pig encephalomyelitis), which itself was named for the town in the Czech Republic where the disease was first recogniaed in 1929.〔(【引用サイトリンク】url=http://viralzone.expasy.org/all_by_species/659.html )〕〔(【引用サイトリンク】title=Virus Taxonomy: 2014 Release )〕〔 ==Genome== ''Teschovirus'' has a single-stranded, linear, non-segmented RNA genome. The RNA genome is positively sensed meaning that it has the same polarity as the mRNA and no reverse transcription is necessary. The size of the genome is between 7000 to 9000 nucleotides long. In addition the virus genome contains at the 5’ end a protein called VPg and the 3’ end is polyadenylated.〔(【引用サイトリンク】url=http://www.dpvweb.net/notes/showgenus.php?genus=Teschovirus )〕 Through translation of the genome a polyprotein is produced. It is later cleaved in order to give twelve proteins. These proteins are nucleoproteins, non-structural proteins, a polymerase, proteases like the leader protein and the genome linked-protein.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Teschovirus」の詳細全文を読む
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