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|Section2= |Section3= }} Tetrazolylglycine (Tet-Gly, LY-285,265) is a potent and selective NMDA receptor agonist, stimulating the NMDA receptor with higher potency than either glutamate or NMDA.〔Lunn WH, Schoepp DD, Calligaro DO, Vasileff RT, Heinz LJ, Salhoff CR, O'Malley PJ. DL-tetrazol-5-ylglycine, a highly potent NMDA agonist: its synthesis and NMDA receptor efficacy. ''Journal of Medicinal Chemistry''. 1992 Nov 27;35(24):4608-12. PMID 1361579〕 It is a potent convulsant and excitotoxin and is used in scientific research.〔Schoepp DD, Smith CL, Lodge D, Millar JD, Leander JD, Sacaan AI, Lunn WH. D,L-(tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist. ''European Journal of Pharmacology''. 1991 Oct 15;203(2):237-43. PMID 1686860〕〔Schoepp DD, Lunn WH, Salhoff CR, McDonald JW. The NMDA receptor agonist DL-(tetrazol-5-yl)glycine is a highly potent excitotoxin. ''European Journal of Pharmacology''. 1994 Jan 3;270(1):67-72. PMID 8157082〕 ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Tetrazolylglycine」の詳細全文を読む スポンサード リンク
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