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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Thrombopoiesis ： ウィキペディア英語版 Thrombopoiesis Thrombopoiesis refers to the process of thrombocyte generation. Thromobocytes are ligations of the cytoplasm from megakaryocytes. A single megakaryocyte can give rise to thousands of thrombocytes. The term "thrombocytopoiesis" is sometimes used to emphasize the cellular nature. Thrombopoietin stimulates megakaryopoiesis, the process of megakaryocyte maturation and differentiation. Thrombopoietin, upon release, binds to its receptor, c-mpl, found on megakaryocyte progenitor cells. Following binding, intracellular signalling leads to megakaryocyte growth, maturation, membrane stability, platelet granule formation and the demarcation of the cytoplasm into regions destined to fragment into mature platelets. These "proplatelet processes" further fragment into platelets. This last step of proplatelet process and platelet formation, ''in vitro'', has been shown to be independent of thrombopoietin. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Thrombopoiesis」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.