翻訳と辞書 Words near each other ・ Thyristor ・ Thymopentin ・ Thymophylla ・ Thymophylla pentachaeta ・ Thymophylla tenuiloba ・ Thymophylla tephroleuca ・ Thymopides ・ Thymopoietin ・ Thymops ・ Thymopsis ・ Thymopsis nilenta ・ Thymoquinone ・ Thymosin beta-4 ・ Thymosin beta-4, Y-chromosomal ・ Thymosin α1 ・ Thymosins ・ Thymosopha ・ Thymovar ・ Thymulin ・ Thymurus ・ Thymus ・ Thymus (disambiguation) ・ Thymus (insect) ・ Thymus (plant) ・ Thymus caespititius ・ Thymus capitatus ・ Thymus carnosus ・ Thymus citriodorus ・ Thymus herba-barona ・ Thymus hyperplasia Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Thymosins ： ウィキペディア英語版 Thymosins Thymosins are small proteins present in many animal tissues. They are named thymosins because they were originally isolated from the thymus, but most are now known to be present in many other tissues. Thymosins have diverse biological activities, and two in particular, thymosins α1 and β4, have potentially important uses in medicine, some of which have already progressed from the laboratory to the clinic. In relation to diseases, thymosins have been categorized as biological response modifiers. == Discovery == The discovery of thymosins in the mid 1960s emerged from investigations of the role of the thymus in development of the vertebrate immune system. Begun by Allan Goldstein in the Laboratory of Abraham White at the Albert Einstein College of Medicine in New York, the work continued at University of Texas Medical Branch in Galveston and at The George Washington University School of Medicine and Health Sciences in Washington D.C. The supposition that the role of the thymus might involve a hormone-like mechanism led to the isolation from thymus tissue of a biologically active preparation. Known as "Thymosin Fraction 5", this was able to restore some aspects of immune function in animals lacking thymus gland. Fraction 5 was found to contain over 40 small peptides (molecular weights ranging from 1000 to 15,000 Da.),〔 which were named "thymosins" and classified as α, β and γ thymosins on the basis of their behaviour in an electric field. Although found together in Fraction 5, they are now known to be structurally and genetically unrelated. Thymosin β1 was found to be ubiquitin (truncated by two C-terminal glycine residues).〔 When individual thymosins were isolated from Fraction 5 and characterized, they were found to have extremely varied and important biological properties. However they are not truly thymic hormones in that they are not restricted in occurrence to thymus and several are widely distributed throughout many different tissues. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Thymosins」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.