翻訳と辞書 Words near each other ・ Tochmarc Étaíne ・ Tochni ・ Tocho language ・ Tochovice ・ Tochołów ・ Tochquonyalla Range ・ Tochtepec (municipality) ・ Tochuhorn ・ Tochuina ・ Tochuina tetraquetra ・ Tochukwu Oluehi ・ Toché (footballer) ・ Tocache District ・ Tocache Province ・ Tocaima ・ Tocainide ・ Tocal, New South Wales ・ Tocaland ・ Tocaloma, California ・ Tocan River ・ Tocancipá ・ Tocando Fondo ・ Tocando Madera ・ Tocane-Saint-Apre ・ Tocantins ・ Tocantins (disambiguation) ・ Tocantins Esporte Clube ・ Tocantins Esporte Clube (TO) ・ Tocantins Futebol Clube ・ Tocantins gubernatorial election, 2010 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Tocainide ： ウィキペディア英語版 Tocainide Tocainide (Tonocard) is a class Ib antiarrhythmic agent. It is no longer sold in the United States. ==Pharmacokinetics== Tocainide is a lidocaine analog, that does not have significant 1st pass metabolism. It is found in two enantiomers. The R isomer is 4x as potent as the S. Oral bioavailability is 0.9-1.0. In the blood tocainide is 10-20% protein bound. The Volume of distribution is 2.5-3.5 L/kg. 30-50% is excreted unchanged in the urine. The more active R-isomer is cleared faster in anephric patients or those with severe renal dysfunction. The main metabolite is the glucuronidated tocainide carbamic acid. The glucuronosyl transferase is apparently induced by rifampin. Weak inhibition of Cyp1A2 leads to a mild theophylline interaction. (Not verbatim) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Tocainide」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.