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Tofogliflozin : ウィキペディア英語版 | Tofogliflozin
Tofogliflozin (USAN, codenamed CSG452) is an experimental drug for the treatment of diabetes mellitus and is being developed by Chugai Pharma in collaboration with Kowa and Sanofi.〔(Chugai Pharmaceutical: Development Pipeline )〕 It is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. , the drug is in Phase III clinical trials. ==Chemistry== ''Tofogliflozin'' is the name of the monohydrate, which is the form used as a drug. The active moiety or anhydrous form (ChemSpider ID: (28530778 ), CHEMBL(2110731 )) has the chemical formula C22H26O6 and a molecular mass of 386.44 g/mol.〔(Statement on a nonproprietary name adopted by the USAN council: Tofogliflozin ).〕
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Tofogliflozin」の詳細全文を読む
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