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Tolevamer
Tolevamer is a toxin binding polymer that was investigated by Genzyme for the treatment of ''Clostridium difficile'' associated diarrhoea (CDAD). ==Background== ''Clostridium difficile'' is a major cause of hospital-acquired diarrhoea, affecting about 300,000 patients in the U.S. alone. CDAD typically occurs after treatment with antibiotics which disrupt the gut flora, allowing ''C. difficile'' to proliferate in the gut and release enterotoxins which lead to diarrhoea. CDAD is usually treated with the antibiotics vancomycin, metronidazole or both. This therapy yields good results but has the disadvantage of further disrupting the flora.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Tolevamer」の詳細全文を読む
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