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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Top7 ： ウィキペディア英語版 Top7 Top7 is an artificial 93-residue protein, classified as a ''de novo'' protein since it was designed by Brian Kuhlman and Gautam Dantas in David Baker's laboratory at the University of Washington to have a unique fold not found in nature. The protein was designed ''ab initio'' on a computer with the help of protein structure prediction algorithms. Determination of the high-resolution X-ray structure of the experimentally expressed and purified protein revealed that the structure (PDB ID: (1QYS )) was indeed very similar (1.2 Å RMSD) to the computer-designed model. The structure consists of two alpha helices packed on a five-stranded anti-parallel beta sheet. Top7 was featured as the RCSB Protein Data Bank's 'Molecule of the Month' in October 2005,〔(【引用サイトリンク】 publisher=RCSB Protein Data Bank )〕 and a superposition of the respective cores (residues 60-79) of its predicted and X-ray crystal structures are featured in the Rosetta@home logo. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Top7」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.