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Trans-splicing : ウィキペディア英語版 | Trans-splicing ''Trans''-splicing is a special form of RNA processing in eukaryotes where exons from two different primary RNA transcripts are joined end to end and ligated. Whereas "normal" (''cis''-)splicing processes a single molecule, ''trans''-splicing generates a single RNA transcript from multiple separate pre-mRNAs. This phenomenon can be exploited for molecular therapy to address mutated gene products. Trans-splicing can be the mechanism behind certain oncogenic fusion transcripts. Trans-splicing is used by certain microbial organisms, notably protozoa of the Kinetoplastae class to produce variable surface antigens and change from one life stage to another. == References ==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Trans-splicing」の詳細全文を読む
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