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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Transcobalamin ： ウィキペディア英語版 Transcobalamin Transcobalamins are carrier proteins which bind cobalamin (B12). ==Types== * Transcobalamin I (TCN1), also known as haptocorrin, R-factor, and R-protein, is a glycoprotein produced by the salivary glands of the mouth. It primarily serves to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a Haptocorrin-Vitamin B12 complex. Once the complex has traveled to the more neutral duodenum, pancreatic proteases degrade haptocorrin, releasing free cobalamin, which now binds to intrinsic factor for absorption by ileal enterocytes. * Transcobalamin II (TCN2) binds cobalamin once it has been uptaken by enterocytes of the terminal ileum and the "Intrinsic Factor-Vitamin B12" complex has been degraded. The TCII-Vit B12 complex then enters portal circulation and is processed in the liver. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Transcobalamin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.