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|Section2= |Section7= }} Trifluorotoluene is an organic compound with the formula of C6H5CF3. This colorless fluorocarbon is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.〔Banks, R.E. Organofluorine Chemicals and their Industrial Applications, Ellis Horwood LTD, Chichester, 1979.〕 ==Synthesis== For small-scale laboratory preparations, trifluorotoluene is synthesized by coupling an aromatic halide and trifluoromethyl iodide in the presence of a copper catalyst:〔Ogawa, Akiya; Tsuchii, Kaname "α,α,α-Trifluorotoluene" in Encyclopedia of Reagents for Organic Synthesis 2005, John Wiley and Sons. 〕 :ArX + CF3I → Ar-CF3 + CuXI (where X = I, Br, Cl) For large scale preparations using batch or continuous processes, benzotrichloride is treated with hydrogen fluoride under pressure.〔Siegemund, Günter "Aromatic Compounds with Fluorinated Side-Chains" in Ullmann’s Encyclopedia of Industrial Chemistry 2005, Wiley-VCH. .〕 :C6H5CCl3 + 3 HF → C6H5CF3 + 3 HCl 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Trifluorotoluene」の詳細全文を読む スポンサード リンク
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