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・ Trifurcula magna
・ Trifurcula manygoza
・ Trifluoromethanesulfonic acid
・ Trifluoromethanesulfonic anhydride
・ Trifluoromethanesulfonyl azide
・ Trifluoromethyl
・ Trifluoromethyl hypofluorite
・ Trifluoromethyl sulphur pentafluoride
・ Trifluoromethylaminoindane
・ Trifluoromethylation
・ Trifluoromethylisocyanide
・ Trifluoromethylphenylpiperazine
・ Trifluoromethylsulfonyl
・ Trifluoromethyltrimethylsilane
・ Trifluorooxonium
Trifluorotoluene
・ Trifluperidol
・ Triflupromazine
・ Trifluralin
・ Trifluridine
・ Trifluridine/tipiracil
・ Triflusal
・ Trifocal
・ Trifocal lenses
・ Trifocal tensor
・ Trifoliate orange
・ Trifolieae
・ Trifolin
・ Trifolium albopurpureum
・ Trifolium alexandrinum


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Trifluorotoluene : ウィキペディア英語版
Trifluorotoluene

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Trifluorotoluene is an organic compound with the formula of C6H5CF3. This colorless fluorocarbon is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.〔Banks, R.E. Organofluorine Chemicals and their Industrial Applications, Ellis Horwood LTD, Chichester, 1979.〕
==Synthesis==
For small-scale laboratory preparations, trifluorotoluene is synthesized by coupling an aromatic halide and trifluoromethyl iodide in the presence of a copper catalyst:〔Ogawa, Akiya; Tsuchii, Kaname "α,α,α-Trifluorotoluene" in Encyclopedia of Reagents for Organic Synthesis 2005, John Wiley and Sons. 〕
:ArX + CF3I → Ar-CF3 + CuXI (where X = I, Br, Cl)
For large scale preparations using batch or continuous processes, benzotrichloride is treated with hydrogen fluoride under pressure.〔Siegemund, Günter "Aromatic Compounds with Fluorinated Side-Chains" in Ullmann’s Encyclopedia of Industrial Chemistry 2005, Wiley-VCH. .〕
:C6H5CCl3 + 3 HF → C6H5CF3 + 3 HCl

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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