翻訳と辞書
Words near each other
・ U. Muthuramalingam Thevar
・ U. N. Biswas
・ U. N. Dhebar
・ U. N. Gunasekera
・ U. Narayan Bhat
・ U. nepalensis
・ U. nitida
・ U. orientalis
・ U. P. Mathaiyan
・ U. R. Ananthamurthy
・ U. R. Bhat
・ U. R. Jeevarathinam
・ U. R. Krishnan
・ U. R. Lalit
・ U. Rama Rao
U-90042
・ U-92,016-A
・ U-Bahn Kontrollöre in tiefgefrorenen Frauenkleidern
・ U-bit
・ U-blox
・ U-boat
・ U-boat (disambiguation)
・ U-boat Campaign (World War I)
・ U-boat Front Clasp
・ U-boat War Badge
・ U-Boat Worx
・ U-bolt
・ U-Boot (beer cocktail)
・ U-Boote westwärts
・ U-Carmen eKhayelitsha


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

U-90042 : ウィキペディア英語版
U-90042

U-90042 is a sedative and hypnotic drug used in scientific research. It has similar effects to sedative-hypnotic benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine hypnotic.
U-90042 is a GABAA agonist acting primarily at the α1, α3 and α6 subtypes, with a Ki of 7.8nM at α1, 9.5nM at α3 and 11.0nM at α6. It produces sedation and ataxia and prolongs sleeping time in mice, rats and monkeys, but does not produce amnesia and blocks the amnestic effect of diazepam, reflecting its different subtype affinity compared to benzodiazepine drugs. It was developed by a team at Novo Nordisk in the 1980s.〔US Patent 5100895 Heterocyclic compounds and their preparation and use〕
== References ==




抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「U-90042」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.