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・ Ube Industries
・ Ube Jinja
・ Ube Kosan Open
・ Ube Line
・ Ube Station
・ Ube, Yamaguchi
・ Ube-Shinkawa Station
・ UBE1C
・ UBE1DC1
・ UBE1L
・ UBE1L2
・ UBE2A
・ UBE2B
・ UBE2C
・ UBE2D1
UBE2D2
・ UBE2D3
・ UBE2E1
・ UBE2E2
・ UBE2E3
・ UBE2G1
・ UBE2G2
・ UBE2H
・ UBE2I
・ UBE2J1
・ UBE2L3
・ UBE2L6
・ UBE2M
・ UBE2N
・ UBE2O


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UBE2D2 : ウィキペディア英語版
UBE2D2

Ubiquitin-conjugating enzyme E2 D2 is a protein that in humans is encoded by the ''UBE2D2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7322 )
== Function ==

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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