翻訳と辞書 Words near each other ・ UBE1L2 ・ UBE2A ・ UBE2B ・ UBE2C ・ UBE2D1 ・ UBE2D2 ・ UBE2D3 ・ UBE2E1 ・ UBE2E2 ・ UBE2E3 ・ UBE2G1 ・ UBE2G2 ・ UBE2H ・ UBE2I ・ UBE2J1 ・ UBE2L3 ・ UBE2L6 ・ UBE2M ・ UBE2N ・ UBE2O ・ UBE2R2 ・ UBE2V1 ・ UBE2V2 ・ UBE3A ・ Ube3a-ATS ・ UBE3C ・ UBE4A ・ UBE4B ・ UBeam ・ Ubee Interactive Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク UBE2L3 ： ウィキペディア英語版 UBE2L3 Ubiquitin-conjugating enzyme E2 L3 is a protein that in humans is encoded by the ''UBE2L3'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7332 )〕 As an E2 enzyme, UBCH7 participates in ubiquitination to target proteins for degradation.〔 The role of UBCH7 in the ubiquitination of the NF-κB precursor implicated it in various major autoimmune diseases, including rheumatoid arthritis (RA), celiac disease, Crohn’s disease(CD), and systemic lupus erythematosus. == Function == The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-κB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.〔 UBE2L3 is primarily known for its role in the cell cycle. Specifically, UBE2L3 manages cell cycle regulatory protein levels via the ubiquitin proteolytic pathway (UPP) during the G1/S transition and during the actual S phase. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「UBE2L3」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.