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UBQLN2
Ubiquilin-2 is a protein that in humans is encoded by the ''UBQLN2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29978 )〕 == Function ==
This gene encodes a ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to effect ''in vivo'' protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「UBQLN2」の詳細全文を読む
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