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・ Udupiddy American Mission College
・ Udupiddy Electoral District
・ Udupiddy Girls' College
・ Udupihilla
・ Udupussallawa railway
・ Udurawana
・ Udurawana Megodagammedda
・ Udurchukan Formation
・ UDP-arabinose 4-epimerase
・ UDP-based Data Transfer Protocol
・ UDP-galactopyranose mutase
・ UDP-galactose—UDP-N-acetylglucosamine galactose phosphotransferase
・ UDP-galacturonate decarboxylase
・ UDP-glucosamine 4-epimerase
・ UDP-glucose 4,6-dehydratase
UDP-glucose 4-epimerase
・ UDP-glucose 6-dehydrogenase
・ UDP-glucose—glycoprotein glucose phosphotransferase
・ UDP-glucose—hexose-1-phosphate uridylyltransferase
・ UDP-glucuronate 4-epimerase
・ UDP-glucuronate 5'-epimerase
・ UDP-glucuronate decarboxylase
・ UDP-glucuronic acid dehydrogenase
・ UDP-Lite
・ UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing)
・ UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
・ UDP-N-acetyl-alpha-D-glucosamine hydro-lyase
・ UDP-N-acetyl-D-mannosamine dehydrogenase
・ UDP-N-acetylgalactosamine diphosphorylase
・ UDP-N-acetylgalactosamine-4-sulfate sulfotransferase


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UDP-glucose 4-epimerase : ウィキペディア英語版
UDP-glucose 4-epimerase

The enzyme UDP-glucose 4-epimerase (), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabolism, catalyzing the reversible conversion of UDP-galactose to UDP-glucose. GALE tightly binds nicotinamide adenine dinucleotide (NAD+), a co-factor required for catalytic activity.
Additionally, human and some bacterial GALE isoforms reversibly catalyze the formation of UDP-''N''-acetylgalactosamine (UDP-GalNAc) from UDP-''N''-acetylglucosamine (UDP-GlcNAc) in the presence of NAD+, an initial step in glycoprotein or glycolipid synthesis.
== Historical significance ==

Dr. Luis Leloir deduced the role of GALE in galactose metabolism during his tenure at the Instituto de Investigaciones Bioquímicas del Fundación Campomar, initially terming the enzyme waldenase. Dr. Leloir was awarded the 1970 Nobel Prize in Chemistry for his discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates.

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