翻訳と辞書 Words near each other ・ Ugrunaaluk ・ Ugruțiu River ・ Ugryumov ・ Ugrzele ・ Ugrós ・ UGS ・ UGS Corp. ・ Ugsarmal bair ・ UGT ・ UGT1A10 ・ UGT1A3 ・ UGT1A4 ・ UGT1A5 ・ UGT1A6 ・ UGT1A7 (gene) ・ UGT1A8 ・ UGT1A9 ・ UGT1A@ ・ UGT2A1 ・ UGT2A2 ・ UGT2B10 ・ UGT2B15 ・ UGT2B17 ・ UGT2B4 ・ UGT2B7 ・ UGT8 ・ Ugtaal ・ UGTAN-unitaire ・ Ugthorpe ・ Ugu Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク UGT1A8 ： ウィキペディア英語版 UGT1A8 UDP-glucuronosyltransferase 1-8 is an enzyme that in humans is encoded by the ''UGT1A8'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54576 )〕 == Function == This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5′ exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity with many substrates including coumarins, phenols, anthraquinones, flavones, and some opioids.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「UGT1A8」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.