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UNC13D
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UNC13D : ウィキペディア英語版
UNC13D

Protein unc-13 homolog D, also known as munc13-4, is a protein that in humans is encoded by the ''UNC13D'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=201294 )
== Function ==

Munc13-4 is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion.
Munc13-4 is an essential protein in the intracellular trafficking and exocytosis of lytic granules. It is targeted to CD63 positive secretory lysosomes. The C-terminal C2 domain of the protein is involved in this process.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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