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Ureidopenicillin : ウィキペディア英語版
Ureidopenicillin

The ureidopenicillins are a group of penicillins which are active against ''Pseudomonas aeruginosa''.
There are three ureidopenicillins in clinical use:〔 〕
*Azlocillin
*Piperacillin
*Mezlocillin
They are mostly ampicillin derivatives in which the amino acid side chain has been converted to a variety of cyclic ureas. It is speculated that the added side chain mimics a longer segment of the peptidoglycan chain, more than ampicillin, and thus would bind more easily to the penicillin-binding proteins. Ureidopenicillins are not resistant to beta-lactamases.
They are used parenterally, and are particularly indicated in infections caused by Gram-negative bacteria.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Ureidopenicillin」の詳細全文を読む



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