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In molecular biology, VR-RNA is a small RNA produced by ''Clostridium perfringens''. It functions as a regulator of the two-component VirR/VirS system. VR-RNA regulates numerous genes including: *Toxin-encoding genes plc, colA and cpb2 *Other virulence-related genes such as hyaluronidases and sialidase *Possible collagen adhesin gene (cna) *Extracellular nuclease, cadA *Enzymes such as Acid phosphatase, Heme oxygenase HemO and N-acetylglucosaminidases *Genes encoding transport proteins *Genes involved in carbohydrate metabolism *Genes encoding transport proteins *Arginine deiminase (ADI) pathway genes *Genes involved in citrate metabolism VR-RNA regulates the toxin colA (collagenase) by base-pairing to colA mRNA, the 3' end of VR-RNA base-pairs to a region in the 5'UTR of the colA mRNA. This induces cleavage of the colA mRNA in the 5' UTR and leads to stabilisation of the mRNA and increased translation. ==See also== *Bacterial small RNA 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「VR-RNA」の詳細全文を読む スポンサード リンク
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