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VU-0238429
VU-0238429 is a drug which acts as a selective positive allosteric modulator for the muscarinic acetylcholine receptor M5. It was the first selective ligand developed for the M5 subtype, and is structurally derived from older M1-selective positive allosteric modulators such as VU-0119498. Replacing the ''O''-methyl- by a phenylgroup further improves the receptor subtype selectivity ((VU-0400265 )). == References ==
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