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Varicellovirus : ウィキペディア英語版 | Varicellovirus
Varicellovirus (var′i-sel′ō-vi′rŭs) is a genus of viruses belonging to subfamily ''Alphaherpesvirinae'', a member of family ''Herpesviridae''. Humans and mammals serve as natural hosts. There are currently 17 species in this genus including the type species Human herpesvirus 3. Diseases associated with this genus include: HHV-3 (also known as Varicella zoster virus) causes chickenpox (varicella) and shingles. BoHV-1 infectious bovine rhinotracheitis / infectious pustular vulvovaginitis (IPV)- SuHV-1 (also known as pseudorabies virus) causes Aujesky's disease characterized by central nervous system signs (hindleg paralysis, meningoencephalitis), high mortality rates in young animals, and respiratory illness in older pigs.〔(【引用サイトリンク】url=http://viralzone.expasy.org/all_by_species/179.html )〕〔(【引用サイトリンク】title=Virus Taxonomy: 2014 Release )〕 == Morphology ==
As with other alphaherpesviruses, the virus particle has a layered structure: Virions consist of an envelope, a tegument, a nucleocapsid, and a core. Tegument is disordered; they do not display a structure and proteins in variable amounts are arranged sometimes in an asymmetric layer located between envelope and capsid. The viral capsid is contained within a spherical envelope which is 120-200 nm in diameter. Surface projections on envelope (viral receptors) are densely dispersed and contain small spikes that evenly dot the surface. The capsid/nucleocapsid is round with triangulation number T=16 and exhibits icosahedral symmetry. The capsid is isometric and has a diameter of 100–110 nm.〔 The capsid consists of 162 capsomer proteins with a hexagonal base and a hole running halfway down the long axis. The core consists of a fibrillar spool on which the DNA is wrapped. The end of the fibers are anchored to the underside of the capsid shell.〔ICTVdB—The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/〕 It is a double-stranded enveloped DNA virus
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