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Vesosome : ウィキペディア英語版
Vesosome

A vesosome is a multi-compartmental structure of lipidic nature used to deliver drugs. They can be considered multivesicular vesicules (MVV)〔Daniels, Rolf. (- Classification, Processing Technologies, Industry Applications and Risk Assessment ) Retrieved 25 November 2012〕

and are, therefore, liposome derived structures.
==Description==
It consists of one or more bilayers enclosing an aqueous core that contains unilamellar vesicles that function as internal compartments which contain the drug and which can vary in composition from each other.
The external bilayer defines the lumen, limits emission of the vesicle contents, and protects the vesicle contents from degradation due to lipolytic enzymes.
Its unique properties enable localized drug delivery in specific parts of the body and extend the duration of drug effect. Also, a vesosome is easy to produce and offers the flexibility to deliver multiple drugs within a single carrier, which has been shown to offer important advantages in chemotherapy.
Internal vesicle diameters range from 20-500 nm and vesosome diameters range from about 0.1 micron to more than 1.0 micron.〔Coldren B, Kennedy MT, Kisak E, Walker SA, Zasadzinski JA (A Versatile Multi-Compartment Structure For Targeted Drug Delivery ) Retrieved 25 November 2012〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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