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Vilazodone
Vilazodone (United States trade name Viibryd ) is a serotonergic antidepressant developed by Clinical Data for the treatment of major depressive disorder. The chemical compound was originally developed by Merck KGaA (Germany). Vilazodone was approved by the FDA for use in the United States to treat major depressive disorder in 2011.〔(【引用サイトリンク】 Clinical Data, Inc. - Clinical Data, Inc. Submits New Drug Application for Vilazodone for the Treatment of Major Depressive Disorder )〕 == Medical uses ==
According to two eight-week, randomized, double-blind, placebo-controlled trials in adults, vilazodone elicits an antidepressant response after one week of treatment. After eight weeks, subjects assigned to vilazodone 40 mg daily dose (titrated over two weeks) experienced a significantly higher response rate than the group given placebo (44% vs 30%, P = .002). Remission rates for vilazodone were not significantly different versus placebo. According to an article on the United States approval of vilazodone written by FDA staff, "it is unknown whether () has any advantages compared to other drugs in the antidepressant class."
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