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Protein KIBRA also known as kidney and brain expressed protein (KIBRA) or WW domain-containing protein 1 (WWC1) is a protein that in humans is encoded by the ''WWC1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23286 )〕 A single nucleotide polymorphism (rs17070145) in the gene has been association with human memory performance in one 2006 study. No significant support for association with memory was found in a study with 584 subjects. However it was replicated in a smaller study of the elderly. A subsequent study in two large UK samples indicated that ''KIBRA'' is specifically associated with forgetting of non-semantic material. Studies have also begun to investigate the role of KIBRA in Alzheimer's disease. == Interactions == ''KIBRA'' has at least 10 interaction partners, including synaptopodin, PKCζ and Dendrin, most of which modify synaptic plasticity. For instance, Dendrin is a post-synaptic protein with expression regulated by sleep deprivation. ''KIBRA'' has been shown to interact with Protein kinase Mζ. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「WWC1」の詳細全文を読む スポンサード リンク
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