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・ WHHI
・ WHHL
・ WHHM-FM
・ WHHN
・ WHHO
・ WHHQ
・ WHHR
・ WHHS
・ WHHS (disambiguation)
・ WHHT
・ WHHV
・ WHHW
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・ WHHZ
・ WHI
Whi2
・ WHI3
・ Whibley
・ WHIC
・ Which
・ Which (Unix)
・ Which Bitch?
・ Which Bridge to Cross (Which Bridge to Burn)
・ Which Doobie U B?
・ Which Face Should I Put On Tonight
・ Which Is Witch
・ Which Lie Did I Tell?
・ Which Medical Device
・ Which Moped with Chrome-plated Handlebars at the Back of the Yard?
・ Which side


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Whi2 : ウィキペディア英語版
Whi2 or Whiskey 2 is a 55 kDa globular,(【引用サイトリンク】url=http://www.yeastrc.org/pdr/yeastProteinRedirect.do?acc=YOR043W
Whi2 or Whiskey 2 is a 55 kDa globular,〔(【引用サイトリンク】url=http://www.yeastrc.org/pdr/yeastProteinRedirect.do?acc=YOR043W#y2hData )〕 cytoplasmatic scaffold protein in Saccharomyces cerevisiae, which plays an essential role in stress response pathways, apparently by passing input signals about nutrient availability on to stress responsive elements and autophagy/mitophagy mechanisms. It is encoded by a 1.46 kbp gene located on chromosome 15.〔(【引用サイトリンク】url=http://www.yeastgenome.org/cgi-bin/locus.fpl?dbid=S000005569 )
== Functional mechanism ==
Upon complexing with plasma membrane associated phosphatase Psr1, Whi2 induces general stress response by dephosphorylating general stress response transcription factor Msn2. Whi2 is essential for Msn2 activity, moreover activation by Whi2 is dominant and independent of the PKA and TOR activation pathways. Additionally, experiments are suggesting Whi2 for playing a role in Ras2 deactivation or degradation during nutrient depletion.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアでWhi2 or Whiskey 2 is a 55 kDa globular,(【引用サイトリンク】url=http://www.yeastrc.org/pdr/yeastProteinRedirect.do?acc=YOR043W」の詳細全文を読む



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