翻訳と辞書 Words near each other ・ XY Notrump convention ・ XY sex-determination system ・ XY TV ・ Xyanide ・ XYAST UAV ・ Xybernaut ・ Xybots ・ Xyclone ・ Xydakis ・ Xydias ・ Xyelacyba myersi ・ Xyelidae ・ Xyeloidea ・ Xygen ・ Xyger ・ Xylamidine ・ Xylan ・ Xylan (coating) ・ Xylan 1,3-b-xylosidase ・ Xylan 1,4-b-xylosidase ・ Xylan alpha-1,2-glucuronosidase ・ Xylan endo-1,3-b-xylosidase ・ Xylanase ・ Xylander ・ Xylanthemum ・ Xylaria ・ Xylaria hypoxylon ・ Xylaria mali ・ Xylaria polymorpha ・ Xylariaceae Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Xylamidine ： ウィキペディア英語版 Xylamidine Xylamidine is a drug which acts as an antagonist at the 5HT2A receptor, and to a lesser extent at the 5HT1A receptor. It does not cross the blood–brain barrier, which makes it useful for blocking peripheral serotonergic responses like cardiovascular and gastrointestinal effects, without producing the central effects of 5HT2A blockade such as sedation, or interfering with the central actions of 5HT2A agonists. ==Synthesis== Xylamidine is an amidine which serves as a serotonin inhibitor. This agent is prepared by alkylation of 3-methoxyphenol (m-methoxyphenol) with α-chloropropionitrile, KI and potassium carbonate in MEK to give #, which is in turn reduced with lithium aluminum hydride to give the primary amine #. When # is treated with m-tolylacetonitrile in the presence of anhydrous HCl, the synthesis is completed. Alternately, one can react primary amine # with m-tolylacetamidine under acid catalysis to produce xylamidine. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Xylamidine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.