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Z-RNA
Z-RNA is a left-handed alternative conformation for the RNA double helix. Just like for Z-DNA, Z-RNA is favored by a sequence composed of Purine/Pyrimidine repeats and especially CG repeats. ==Discovery== The ability of dsRNA to convert into a left-handed helix was demonstrated using NMR and circular dichroism in 1984.〔Hall, K., P. Cruz, I. Tinoco, Jr., T.M. Jovin, and J.H. van de Sande, 'Z-RNA'--a left-handed RNA double helix. Nature, 1984. 311(5986): p. 584-6.〕 This conversion was shown to require high ionic strength and elevated temperatures (35 degrees).
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Z-RNA」の詳細全文を読む
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