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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ZC3HC1 ： ウィキペディア英語版 ZC3HC1 Nuclear-interacting partner of ALK is a protein that in humans is encoded by the ''ZC3HC1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51530 )〕 ==Model organisms== Model organisms have been used in the study of ZC3HC1 function. A conditional knockout mouse line, called ''Zc3hc1tm1a(KOMP)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔 Twenty two tests were carried out on mutant mice and eleven significant abnormalities were observed.〔 Fewer than expected homozygous mutant mice were identified at weaning. Mutants appear to be subfertile, had decreased vertical activity in an open field, decreased lean body mass, decreased rib number and decreased mature B cell number. Males also had a decreased body weight, an abnormal posture and atypical indirect calorimetry data. Females also had an abnormally short snout and atypical haematology parameters .〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ZC3HC1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.