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ZFAT-AS1 In molecular biology, ZFAT antisense RNA 1 (non-protein coding), also known as ZFAT-AS1, is a long non-coding RNA. In peripheral blood lymphocytes, it is expressed in CD19+ B-cells.〔 〕 It is an antisense transcript of the ZFAT gene, and negatively regulates the expression of a truncated form of ZFAT, TR-ZFAT, but not of ZFAT.〔 A single nucleotide polymorphism (SNP) which is located in the 3'-UTR of TR-ZFAT and the promoter region of ZFAT-AS1 regulates the expression of ZFAT-AS1, and therefore also affects expression of TR-ZFAT. This SNP is associated with an increased risk of autoimmune thyroid disease.〔 ==See also==
* Long noncoding RNA
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「ZFAT-AS1」の詳細全文を読む
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