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ZNF837
ZNF837 is a protein that in humans is encoded by the ZNF837 gene, is located at 19q13.431 with minus strand orientation.〔http://www.ncbi.nlm.nih.gov/gene/116412〕 ZNF837 protein is characterized as a C2H2-type zinc finger protein. ==Homology and Evolution==
The human ZNF837 has homologs present in many mammals and seen more distantly. All homologs are chordates. All contain both COG5048 and Zf-C2H2_2 domains. The areas that these domains are found contain the highest conservation rates. In humans, 5 Zf-H2C2 double domains and 2 COG5048 domains〔http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi?RID=F6ZGBE9S01R&mode=all〕 are present. The protein sequence is fast evolving among these homologs. ZNF837 has numerous paralogs in humans, all of which are zinc finger proteins.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「ZNF837」の詳細全文を読む
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