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Zenarestat (FK-366; FR-74366) is an aldose reductase inhibitor. It was intended to be used in the treatment of diabetic neuropathy and cataract. ==References== * M. Hashimoto et al., EP 218999; eidem, US 4734419 (1987, 1988 both to Fujisawa) * Inhibition kinetics and effect on sorbitol accumulation: S. Ao et al., Metabolism 40, 77 (1991) *Pharmacokinetics and metabolism in diabetic rats: Y. Tanaka et al., Drug Metab. Dispos. 21, 677 (1993) * M. Kanamaru et al., J. Clin. Pharmacol. 33, 1122 (1993). 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Zenarestat」の詳細全文を読む スポンサード リンク
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