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Zicronapine
Zicronapine (, previously known as Lu 31-130) is an atypical antipsychotic medication formerly under development by H. Lundbeck A/S. In phase II studies zicronapine showed statistically significant separation from placebo and convincing efficacy and safety data when compared to olanzapine.〔(【引用サイトリンク】url=http://investor.lundbeck.com/releasedetail.cfm?ReleaseID=608573 )〕 In 2014 Lundbeck removed zicronapine from its development portfolio in favor of pursuing the more promising medicine Lu AF35700. 〔(【引用サイトリンク】url=http://www.euroinvestor.dk/pdf/cse/2015/02/13101242/Lundbeck%20FY2014%20Results.pdf )〕 Zicronapine exhibits monoaminergic activity and has a multi-receptorial profile. ''In vitro'' and ''in vivo'' it has shown potent antagonistic effects at dopamine D1, D2 and serotonin 5HT2A receptors.〔(【引用サイトリンク】url=http://investor.lundbeck.com/releasedetail.cfm?ReleaseID=608605 )〕 ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Zicronapine」の詳細全文を読む
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