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adenylosuccinate : ウィキペディア英語版
adenylosuccinate

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Adenylosuccinate is an intermediate in the interconversion of purine nucleotides inosine monophosphate (IMP) and adenosine monophosphate (AMP). The enzyme adenylosuccinate synthase carries out the reaction by the addition of aspartate to IMP and requires the input of energy from a phosphoanhydride bond in the form of guanosine triphosphate (GTP).〔Figures 20.4 and 20.7 in ''Textbook of Biochemistry'', with clinical correlations, Sixth Edition, Thomas M. Devlin, Ed., Wiley-Liss, Inc., New York, NY, 2006〕 GTP is used instead of ] (ATP), so the reaction is not dependent on its products.
==See also==

* Adenylosuccinate lyase deficiency
* Purine nucleotide cycle

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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