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amatoxin : ウィキペディア英語版
amatoxin
Amatoxins are a subgroup of at least eight toxic compounds found in several genera of poisonous mushrooms, most notably ''Amanita phalloides'' and several other members of the genus ''Amanita'', as well as some ''Conocybe'', ''Galerina'' and ''Lepiota'' mushroom species.
==Structure==
The compounds have a similar structure, that of eight amino-acid residues arranged in a conserved macrobicyclic motif (an overall pentacyclic structure when counting the rings inherent in the proline and tryptophan-derived residues); they were isolated in 1941 by Heinrich O. Wieland and Rudolf Hallermayer. All amatoxins are oligopeptides that are synthesized as 35-amino-acid proproteins, from which the final eight amino acids are cleaved by a prolyl oligopeptidase.
There are currently ten known amatoxins:
δ-Amanitin has been reported, but its chemical structure has not been determined.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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