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anisomycin : ウィキペディア英語版
anisomycin

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Anisomycin, also known as flagecidin, is an antibiotic produced by ''Streptomyces griseolus'' which inhibits protein synthesis. Partial inhibition of DNA synthesis occurs at anisomycin concentrations that effect 95% inhibition of protein synthesis. Anisomycin can activate stress-activated protein kinases, MAP kinase and other signal transduction pathways.
Anisomycin is inactive against bacteria.
==Pharmacology==
Anisomycin interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
Anisomycin is also mentioned as a potential psychiatric drug, as it may inhibit the consolidation of new context-specific long-term memories."., as well as long time consolidated memories rendered labile through reactivation.〔Debiec et al, Neuron, 2002. PMID 12408854〕
Injection of anisomycin into the hippocampus has been proposed for selective removal of memories.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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