| 翻訳と辞書 |
anoikis
Anoikis is a form of programmed cell death that is induced by anchorage-dependent cells detaching from the surrounding extracellular matrix (ECM). Usually cells stay close to the tissue to which they belong since the communication between proximal cells as well as between cells and ECM provide essential signals for growth or survival. When cells are detached from the ECM, there is a loss of normal cell–matrix interactions, and they may undergo anoikis. However, metastatic tumor cells may escape from anoikis and invade other organs.
==Etymology==
The word Anoikis was coined by Frisch and Francis in a paper published in the Journal of Cell Biology in 1994. Anoikis, in their words, means "(...the state of being without a home) to describe the cells' apoptotic response to the absence of cell–matrix interactions." The word apparently is a neologism construction consisting of three Greek morphemes agglutinated together: ἀν- "without", οἰκ- "house", and -ις (extracted from -σις "trait, attribute"; confer apo-pto-sis "state of being fallen off").
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「anoikis」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|