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ansamycin
Ansamycins is a family of secondary metabolites that show antimicrobial activity against many Gram-positive and some Gram-negative bacteria and includes various compounds, among which: streptovaricins and rifamycins. In addition, these compounds demonstrate antiviral activity towards bacteriophages and poxviruses.
==Structure==
They are named ansamycins (from the Latin ansa, ''handle'') because of their unique structure, which comprises an aromatic moiety bridged by an aliphatic chain. The main difference between various derivatives of ansamycins is the aromatic moiety, which can be a naphthalene ring or a naphthoquinone ring as in rifamycin and the naphthomycins. Another variation comprises benzene or a benzoquinone ring system as in geldanamycin or ansamitocin. Ansamycins were first discovered in 1959 by Sensi et al. from ''Amycolatopsis mediterranei'', an actinomycete.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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