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apocrine
Apocrine is a term used to classify exocrine glands in the study of histology. Cells which are classified as apocrine bud their secretions off through the plasma membrane producing membrane-bound vesicles in the lumen.The apical portion of the secretory cell of the gland pinches off and enters the lumen. It loses part of its cytoplasm in their secretions. Apocrine glands are found around armpits & the nipples and the groin regions of the body. Apocrine is functional during hormonal stress or puberty.
Secretion occurs when the release of secretory materials is accompanied with loss of part of cytoplasm. Apocrine secretion is less damaging to the gland than holocrine secretion (which destroys a cell) but more damaging than merocrine secretion (exocytosis).
An example of true apocrine glands are mammary glands, responsible for secreting breast milk.〔Mescher AL, "Chapter 4. Epithelial Tissue" (Chapter). Mescher AL: Junqueira's Basic Histology: Text & Atlas, 12e: http://www.accessmedicine.com/content.aspx?aID=6180489.〕
==Apocrine Metaplasia==
(詳細はphenotype. It is common in the breast in the context of fibrocystic change. It is seen in women mostly over the age of 50 years. Metaplasia happens when there is an irritation to the breast (breast cyst). Apocrine-like cells form in a lining of developing microcysts, due to the pressure buildup within the lumen. The pressure build up is caused by secretions.〔Dr Ayush Goel and Radswiki et al. Apocrine metaplasia of the breast.http://radiopaedia.org/articles/apocrine-metaplasia-of-the-breast〕 The chance of developing breast cancer increases when metaplasia proliferates.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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