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Azacyclonol (trade names Ataractan, Calmeran, Frenoton, Frenquel, Psychosan), also known as γ-pipradol, is a drug which is a so-called ataractive, or agent which diminishes hallucinations in psychotic individuals. It has also been called a tranquilizer and antipsychotic, though these definitions are not accurate as it does not actually possess such properties. Despite being a positional isomer of pipradrol, it is not a psychostimulant, and instead has mild depressant effects.〔 The drug was introduced in Europe in the mid-1950s for the treatment of schizophrenia likely because it was found to attenuate the subjective psychedelic effects of LSD and mescaline in humans.〔 However, due to poor and mixed clinical effectiveness〔 it never gained widespread acceptance and was eventually discontinued. The antihistamine agent terfenadine produces azacyclonol as an active major metabolite. It is made by the organometallic addition of 4-bromopyridine to benzophenone, followed by catalytic hydrogenation of the pyridine heteroaromatic ring system to the corresponding piperidine.〔Campen Jr Marcus G Van, Pogge Raymond C, Schumann Edward L; Wm S Merrell Co; (1957).〕 ==See also== * Pipradrol * Terfenadine * Fexofenadine 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「azacyclonol」の詳細全文を読む スポンサード リンク
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