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basophilia
Basophilia is a condition where the basophil quantity is abnormally elevated (more than 1010 basophils per liter of blood).
==Causes==
Basophilia as an isolated finding is uncommon. However it is a common feature of myeloproliferative disorders and particularly prominent in chronic myelogenous leukemia.〔Table 12-6 in: 8th edition.〕
Conditions Associated with Alterations in Numbers of Blood Basophils
I. Decreased Numbers (Basopenia)
A. Hereditary absence of basophils (very rare)
B. Elevated levels of glucocorticoids
C. Hyperthyroidism or treatment with thyroid hormones
D. Ovulation
E. Hypersensitivity reactions
1. Urticaria
2. Anaphylaxis
3. Drug-induced reactions
F. Leukocytosis (in association with diverse disorders)
II. Increased Numbers (Basophilia)
A. Allergy or inflammation
1. Ulcerative colitis
2. Drug, food, inhalant hypersensitivity
3. Erythroderma, urticaria
4. Juvenile rheumatoid arthritis
B. Endocrinopathy
1. Diabetes mellitus
2. Estrogen administration
3. Hypothyroidism (myxedema)
C. Infection
1. Chicken pox
2. Influenza
3. Smallpox
4. Tuberculosis
D. Iron deficiency
E. Exposure to ionizing radiation
F. Neoplasia
1. "Basophilic leukemia" (see text)
G. Myeloproliferative neoplasms (especially chronic myelogenous leukemia; also polycythemia vera, primary myelofibrosis, essential thrombocythemia)
H. Carcinoma
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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