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bestoxin
Bestoxin is a neurotoxin from the venom of the South African spitting (or fattail) scorpion ''Parabuthus transvaalicus''. Most likely, it targets sodium channel function, thus promoting spontaneous and repetitive neuronal firing. Following injection into mice, it causes non-lethal writhing behaviour.
== Source ==
Bestoxin is one of the many components that can be isolated from the venom of the South African spitting scorpion. Other peptide toxins also found in the venom include dortoxin, birtoxin, and altitoxin. Together with birtoxin, dorotoxin, altitoxin and ikitoxin, this mammal-specific ion channel toxin is a member of the birtoxin polypeptide family. These birtoxin-like polypeptides contribute significantly to the venom’s toxicity, since they constitute at least 30% of the peptides in the venom of this scorpion.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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